BDBM50613758 CHEMBL5286183

SMILES [H][C@]12CCCCN1CCC[C@H]2CCNc1ccc(C)c2sc3ccccc3c(=O)c12

InChI Key InChIKey=BENIBYVETVNODM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50613758   

TargetMicrotubule-associated protein tau(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50613758(CHEMBL5286183)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of tau (unknown origin) aggregation expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50613758(CHEMBL5286183)
Affinity DataIC50: 840nMAssay Description:Inhibition of amyloid beta 40 peptide (unknown origin) aggregation incubated for 2 hr by ThT fluorescence based spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50613758(CHEMBL5286183)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50613758(CHEMBL5286183)
Affinity DataIC50: 460nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50613758(CHEMBL5286183)
Affinity DataIC50: 840nMAssay Description:Inhibition of self-induced amyloid beta (unknown origin) aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed