BDBM50613729 CHEMBL5282411

SMILES OC(Cn1ccnc1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc12

InChI Key InChIKey=BKMVULRFIQMMNO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50613729   

TargetThyrotropin receptor(Rat)
Pcovery

Curated by ChEMBL
LigandPNGBDBM50613729(CHEMBL5282411)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae H+ ATPase pma1 isoform assessed as ATP hydrolysis incubated for 30 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Rat)
Pcovery

Curated by ChEMBL
LigandPNGBDBM50613729(CHEMBL5282411)
Affinity DataIC50: 7.80E+4nMAssay Description:Allosteric inhibition of H+ ATPase pma1 isoform by measuring NADP-coupled ATPase activity in presence of 1 mM ATP by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetThyrotropin receptor(Rat)
Pcovery

Curated by ChEMBL
LigandPNGBDBM50613729(CHEMBL5282411)
Affinity DataIC50: 6.00E+4nMAssay Description:Allosteric inhibition of H+ ATPase pma1 isoform by measuring NADP-coupled ATPase activity in presence of 10 mM ATP by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed