BDBM50613464 CHEMBL5278351

SMILES COc1ccc2-c3c(C)noc3[C@H](CC(N)=O)N=C(c3ccc(Cl)cc3)c2c1

InChI Key InChIKey=PIUIYDIJKKQYAX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50613464   

TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613464(CHEMBL5278351)
Affinity DataEC50:  64nMAssay Description:Inhibition of BRD4 BD1 in human MV4-11 cells assessed as reduction of MYC RNA expression after 4 hrs by PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50613464(CHEMBL5278351)
Affinity DataIC50: 17nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotinylated ligand incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed