BDBM50613319 CHEMBL5273771

SMILES Oc1ccc(c(c1)-c1ncc2c(nc(OCC34CCCN3CCC4)nc2c1F)N1CC2CCC1CN2)C(F)(F)F

InChI Key InChIKey=RCMYFUXLENTYTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50613319   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50613319(CHEMBL5273771)
Affinity DataIC50: 1nMAssay Description:Inhibition of human KRAS G12D mutant in human AGS cells assessed as reduction in phosphorylated ERK level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed