BDBM50613318 CHEMBL5290757

SMILES Oc1cc(Cl)c(c(c1)-c1ncc2c(nc(OCC34CCCN3CCC4)nc2c1F)N1CC2CCC1CN2)C(F)(F)F

InChI Key InChIKey=RAJWEESLEYHKEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50613318   

TargetGTPase KRas(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50613318(CHEMBL5290757)
Affinity DataIC50: 1nMAssay Description:Inhibition of human KRAS G12D mutant in human AGS cells assessed as reduction in phosphorylated ERK level incubated for 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed