BDBM50613306 CHEMBL1235645

SMILES N#CCc1ccc(Nc2nccc(Nc3cc([nH]n3)C3CC3)n2)cc1

InChI Key InChIKey=YRRRHSNOXWKVDL-UHFFFAOYSA-N

Data  5 IC50  3 Kd  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50613306   

TargetTGF-beta receptor type-1(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataKd:  324nMAssay Description:Inhibition of ALK5 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataKd:  186nMAssay Description:Inhibition of BMPR2 (unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-2(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 36nMAssay Description:Inhibition of BMPR2 (174 to end residues) (unknown origin) using MBP as substrate incubated for 60 mins in presence of ATP by ADP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal NanoLuc-fused full length GSK3A (unknown origin) transfected in HEK293T cells incubated for 2 hrs in presence of tracer K8 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of N-terminal NanoLuc-fused full length intact GSK3B (unknown origin) transfected in HEK293T cells incubated for 2 hrs in presence of trac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal NanoLuc-fused full length lysed GSK3B (unknown origin) transfected in HEK293T cells incubated for 2 hrs in presence of trace...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataKd:  186nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 4(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataEC50:  200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 3(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataEC50:  110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataEC50:  6.54E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 26(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataEC50:  4.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataEC50:  280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 26(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50613306(CHEMBL1235645)
Affinity DataEC50:  230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed