BDBM50613099 CHEMBL5288212

SMILES Cc1c(c(c([nH]1)C(=O)Nc2nc3c(cc(cc3s2)C(=O)O)N4CCOCC4)Cl)Cl

InChI Key InChIKey=XMRMYIYEEWALOZ-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50613099   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoilingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 decatenation incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: 10nMAssay Description:Inhibition of Pseudomonas aeruginosa DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50613099(CHEMBL5288212)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alpha relaxationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed