BDBM50613033 CHEMBL5279691

SMILES Cc1cc(nc(Nc2ccccc2-c2nnn[nH]2)n1)C(F)(F)F

InChI Key InChIKey=XXKGCSWBGJTTJM-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50613033   

TargetTaste receptor type 2 member 14(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataEC50:  72nMAssay Description:Agonist activity at human TAS2R14 transfected in HEK293T cells assessed as IP1 accumulation measured after 150 mins by IP1 accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]NMS from human M2 receptor stably expressed in HEK293T cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  7.30E+3nMAssay Description:Displacement of [3H]methylspiperone from human D2S receptor stably expressed in CHO cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander-Universitat Erlangen-Nurnberg

Curated by ChEMBL
LigandPNGBDBM50613033(CHEMBL5279691)
Affinity DataKi:  1.60E+4nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor stably expressed in CHO cells by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed