BDBM50612722 CHEMBL5268914

SMILES CN(CCCO)c1ccc(\C=C2\N(C)C(=S)N(C3CCCCC3)C2=O)c(O)c1

InChI Key InChIKey=DCZOFUZQBABTJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612722   

TargetNADPH oxidase 4(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50612722(CHEMBL5268914)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human NOX4 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome b-245 heavy chain(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50612722(CHEMBL5268914)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed