BDBM50612713 CHEMBL5271584

SMILES COc1cc(ccc1\C=C1\N(C)C(=S)N(C1=O)c1ccccc1)N(C)CCO

InChI Key InChIKey=PWMRZQQUPHANSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612713   

TargetNADPH oxidase 4(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50612713(CHEMBL5271584)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of human NOX4 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome b-245 heavy chain(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50612713(CHEMBL5271584)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of human NOX2 assessed as reduction in ROS production using lucigenin as substrate in presence of NADPH by chemiluminescence based micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed