BDBM50612445 CHEMBL5282110

SMILES CCC(=O)CCCCC[C@H](NC(=O)C12CCN(CC1)CC2)c1ncc(o1)-c1cc2ccccc2nc1OC

InChI Key InChIKey=NBVPHNBDESFHFB-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50612445   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612445(CHEMBL5282110)
Affinity DataEC50:  43nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612445(CHEMBL5282110)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612445(CHEMBL5282110)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612445(CHEMBL5282110)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human HDAC3 expressed in baculovirus infected insect cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612445(CHEMBL5282110)
Affinity DataIC50: 190nMAssay Description:Inhibition of hERG potassium channel incubated for 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed