BDBM50612441 CHEMBL5268555

SMILES CNC(=O)CCCCC[C@H](NC(=O)Cn1ccc2cc(ccc12)C#N)c1ncc([nH]1)-c1ccc(CN(C)C)cc1

InChI Key InChIKey=WNBJBSFSPKVIPC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50612441   

TargetHistone deacetylase 3(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant his tagged HDAC3 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
IRBM Science Park

Curated by ChEMBL
LigandPNGBDBM50612441(CHEMBL5268555)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed