BDBM50612196 CHEMBL5281809

SMILES [H][C@@]12CN(C)[C@@]([H])(C[C@H]1n1cc(Nc3nc(OC4(C)CC4)c4nc(c(F)cc4n3)-c3cnc(C)nc3)cn1)C2

InChI Key InChIKey=REFNAHFTYXTJKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612196   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612196(CHEMBL5281809)
Affinity DataIC50: 32nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612196(CHEMBL5281809)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed