BDBM50612175 CHEMBL5266602

SMILES Cn1cc(Nc2nc(NC3CC3)c3nc(CC#N)ccc3n2)cn1

InChI Key InChIKey=VNAXLUYLDVAZEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612175   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612175(CHEMBL5266602)
Affinity DataIC50: 22nMAssay Description:Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50612175(CHEMBL5266602)
Affinity DataIC50: 490nMAssay Description:Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed