BDBM50612148 CHEMBL5289136

SMILES [O-]S(=O)(=O)Oc1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=MAYYSIZGYJEIHD-UHFFFAOYSA-M

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50612148   

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50612148(CHEMBL5289136)
Affinity DataIC50: 3.75E+5nMAssay Description:Inhibition of human FXIa using S-2366 as chromogenic substrate preincubated with enzyme for 10 mins followed by substrate addition by spectrophotomet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50612148(CHEMBL5289136)
Affinity DataKd:  3.65E+5nMAssay Description:Binding affinity to active site dansylated human DEGR-FXIa assessed as change in fluorescence intensity by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed