BDBM50612045 CHEMBL5286745

SMILES O=C(NCCN1CCOCC1)Nc1nc2ccc(Sc3nnc4ccc(nn34)-c3ccccc3)cc2s1

InChI Key InChIKey=WTVCPJCTIVZLQJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50612045   

TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human MET incubated for 30 mins in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human MET H1094Y mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human MET Y1235D mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human MET M1250T mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 65nMAssay Description:Inhibition of human MET L1195V mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50612045(CHEMBL5286745)
Affinity DataIC50: 81nMAssay Description:Inhibition of human MET D1228H mutant incubated for 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed