BDBM50611784 CHEMBL5276430

SMILES N[C@H]1C[C@H](CO[C@@H]1c1cc(F)ccc1F)N1CC2=C(C1)CS(=O)(=O)C2

InChI Key InChIKey=ROFOCLOPXHFEIE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50611784   

TargetDipeptidyl peptidase 4(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50611784(CHEMBL5276430)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to human recombinant DPP-4 using H-Gly-Pro-AMC as substrate assessed as inhibition constant measured after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50611784(CHEMBL5276430)
Affinity DataKi:  5.5nMAssay Description:Inhibition of human recombinant DPP4 using Gly-Pro-7-amido-4-methylcoumarin hydrobromide as substrate incubated for 30 mins by fluorescence microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50611784(CHEMBL5276430)
Affinity DataKi:  1.90E+4nMAssay Description:Binding affinity to human recombinant DPP-9 using H-Gly-Pro-AMC as substrate assessed as inhibition constant measured after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50611784(CHEMBL5276430)
Affinity DataKi:  1.95E+4nMAssay Description:Inhibition of human recombinant DPP9 using Gly-Pro-7-amido-4-methylcoumarin hydrobromide as substrate incubated for 30 mins by fluorescence microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50611784(CHEMBL5276430)
Affinity DataKi:  3.70E+4nMAssay Description:Binding affinity to human recombinant DPP-8 using H-Gly-Pro-AMC as substrate assessed as inhibition constant measured after 30 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50611784(CHEMBL5276430)
Affinity DataKi:  3.75E+4nMAssay Description:Inhibition of human recombinant DPP8 using Gly-Pro-7-amido-4-methylcoumarin hydrobromide as substrate incubated for 30 mins by fluorescence microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed