BDBM50611541 CHEMBL5269844::US20240246937, Example 27

SMILES Fc1cccc(c1)-c1nnc(CN2CCN(C3CCC3)C(=O)C2=O)s1

InChI Key InChIKey=RJXWYHAEAYADEC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50611541   

TargetInterleukin-1 receptor antagonist protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50611541(CHEMBL5269844 | US20240246937, Example 27)
Affinity DataEC50:  5nMAssay Description:Using this assay, the potency (EC50) of each compound was determined from a ten-point (1:3 serial dilution) titration curve using the following outli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetL-amino-acid oxidase(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50611541(CHEMBL5269844 | US20240246937, Example 27)
Affinity DataEC50:  5nMAssay Description:Inhibition of C-terminal 6-His tagged recombinant human IL4I1 (Gln22 to His567 residues) expressed in CHO cells using Phe/Tyr/Trp as substrate assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed