BDBM50611436 CHEMBL5287234

SMILES CCN(Cc1cc(C)n(CC2(CC2)C#N)c(=O)c1)c1ccc(F)cc1

InChI Key InChIKey=DEKUOCRSJJSHDK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50611436   

TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611436(CHEMBL5287234)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGlutamate receptor 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50611436(CHEMBL5287234)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed