BDBM50611391 CHEMBL5274065

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1ccc(-[#8])c(-[#6](=O)-c2c(-[#8])cc(-[#6])cc2-[#6]-2=[#6](-c3c(cc(-[#6])cc3-[#8])-[#6]-2=O)-c2c(-[#8])ccc(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8])c1-[#8]

InChI Key InChIKey=CMHDANQLOFOUEK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50611391   

TargetSterol O-acyltransferase 1(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50611391(CHEMBL5274065)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human SOAT1 expressed in mouse AC29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 2(Human)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50611391(CHEMBL5274065)
Affinity DataIC50: 69nMAssay Description:Inhibition of human SOAT2 expressed in mouse AC29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Green monkey)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50611391(CHEMBL5274065)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of african green monkey SOAT1 expressed in CHO cells assessed as reduction cholesteryl ester synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSterol O-acyltransferase 2(Green monkey)
National Institute On Alcohol Abuse and Alcoholism

Curated by ChEMBL
LigandPNGBDBM50611391(CHEMBL5274065)
Affinity DataIC50: 150nMAssay Description:Inhibition of african green monkey SAOT2 in CHO cells assessed as reduction cholesteryl ester synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed