BDBM50611031 CHEMBL5266303

SMILES CC[C@@H](Nc1c(C#N)c(nc2cnccc12)-c1ccc(cc1)-c1cccc(F)c1)C(N)=O

InChI Key InChIKey=YJGGIMYNVZOKRK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50611031   

TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
Bayer

Curated by ChEMBL

LigandBDBM50611031(CHEMBL5266303)Copy SMILESCopy InChI

Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant full length His-tagged PIP4K2A (unknown origin) expressed in sf21 cells assessed as reduction in ADP production preincubate...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
Bayer

Curated by ChEMBL

LigandBDBM50611031(CHEMBL5266303)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PIP4K2A in human THP-1 cells assessed as increase in Akt phosphorylation at Ser473 residue incubated for 2 hrs by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/21/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL