BDBM50610852 CHEMBL5287835

SMILES COc1ccc(c2ncccc12)S(=O)(=O)Nc1ccccc1C#Cc1ccc(cc1)C(O)=O

InChI Key InChIKey=MENPFOQPGOROOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50610852   

TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610852(CHEMBL5287835)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610852(CHEMBL5287835)
Affinity DataIC50: 21nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)gluc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610852(CHEMBL5287835)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of radioactive lactate efflux preincubated for 30 mins followed by D(+)glucose...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610852(CHEMBL5287835)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MCT4 in human SNU-398 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed