BDBM50610829 CHEMBL5288904

SMILES Cc1cc(c2ncccc2c1)S(=O)(=O)Nc1ccccc1C#Cc1ccc(nc1)C(O)=O

InChI Key InChIKey=DFRAPHVFURUQSM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50610829   

TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610829(CHEMBL5288904)
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610829(CHEMBL5288904)
Affinity DataIC50: 243nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMonocarboxylate transporter 4(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50610829(CHEMBL5288904)
Affinity DataKi:  51nMAssay Description:Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed