BDBM50610599 CHEMBL5275972

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)-c2nc3ccc(cc3n2[C@@H](C)c2ccc(F)cc2)C(F)(F)F)cc1

InChI Key InChIKey=KPMTUCCYXWPTAN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50610599   

TargetBile acid receptor(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50610599(CHEMBL5275972)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human GAL4-fused FXR LBD transfected in 293T cell measured after 24 hrs by dual luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50610599(CHEMBL5275972)
Affinity DataIC50: 64nMAssay Description:Inverse agonist activity at human GAL4-fused RORgamma LBD (262 to 507 residues) transfected in HEK293T cell measured after 24 hrs by dual luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50610599(CHEMBL5275972)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human GAL4-fused LXRalpha LBD transfected in 293T cell measured after 24 hrs by dual luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNuclear receptor ROR-beta(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50610599(CHEMBL5275972)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human GAL4-fused RORbeta LBD transfected in 293T cell measured after 24 hrs by dual luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetNuclear receptor ROR-alpha(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50610599(CHEMBL5275972)
Affinity DataIC50: 2.00E+4nMAssay Description:Inverse agonist activity at human GAL4-fused RORalpha LBD transfected in 293T cell measured after 24 hrs by dual luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed