BDBM50610594 CHEMBL5290398

SMILES CN(C)CCCNc1nc(NC2CCN(Cc3ccccc3)CC2)c2ccccc2n1

InChI Key InChIKey=OVNOBEWSTIRPLG-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50610594   

TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataKd:  385nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human G9a expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of human LSD1 (unknown orgin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataKd:  385nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Xinxiang University

Curated by ChEMBL
LigandPNGBDBM50610594(CHEMBL5290398)
Affinity DataKi:  1.06E+3nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed