BDBM50610445 CHEMBL5283177

SMILES Cc1cccc2c(c[nH]c12)C(=O)N1CCN(Cc2ccc(cc2)C(=O)NO)CC1

InChI Key InChIKey=LOYLSJNIQXFWSL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50610445   

TargetHistone deacetylase 1(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50610445(CHEMBL5283177)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50610445(CHEMBL5283177)
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50610445(CHEMBL5283177)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50610445(CHEMBL5283177)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide RHKKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50610445(CHEMBL5283177)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using trifluoroacetyl lysine as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50610445(CHEMBL5283177)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide RHKAcKAc-AMC as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed