BDBM50610347 CHEMBL5287675

SMILES Cc1cc(nc(n1)N1CCCC1)N1CCN(CC1)C(=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=SKGMZKDWWUMKLB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50610347   

TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50610347(CHEMBL5287675)
Affinity DataEC50:  100nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed