BDBM50610151 CHEMBL5282181

SMILES COc1ccccc1CNC(=O)c1ccc(Cl)c(c1)C(=O)Nc1ccccc1

InChI Key InChIKey=UPACSVRRIRUWJK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610151   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610151(CHEMBL5282181)
Affinity DataEC50:  2.73E+3nMAssay Description:Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610151(CHEMBL5282181)
Affinity DataIC50: 2.20E+3nMAssay Description:Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed