BDBM50610149 CHEMBL5272116

SMILES Cc1cc(cc(C(=O)Nc2ccccc2)c1Cl)C(=O)NCc1ccccc1

InChI Key InChIKey=NYRKZLNNDOGSQB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50610149   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610149(CHEMBL5272116)
Affinity DataEC50: >3.30E+4nMAssay Description:Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50610149(CHEMBL5272116)
Affinity DataIC50: 5.00E+3nMAssay Description:Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed