BDBM50610097 CHEMBL5273198

SMILES Cc1ccc(cc1C)Sc2cc(ccc2O)C(=O)N3Cc4ccccc4C3

InChI Key InChIKey=AXEQZLWHIYQNKM-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50610097   

TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50610097(CHEMBL5273198)
Affinity DataIC50: 840nMAssay Description:Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50610097(CHEMBL5273198)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to HSP90beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50610097(CHEMBL5273198)
Affinity DataKd:  840nMAssay Description:Binding affinity HSP90alpha (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-beta(Human)
The University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50610097(CHEMBL5273198)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity HSP90beta (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed