BDBM50609721 CHEMBL5270408

SMILES COc1c(cc(cc1Cl)[C@@H]2c3cc4c(cc3C[C@@H]5N2C(=O)NC5=O)OCCO4)Cl

InChI Key InChIKey=GANPPQNYXDZLNS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609721   

TargetTubulin beta chain(Pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609721(CHEMBL5270408)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of porcine brain tubulin assessed as changes in the fluorescence intensity measured for 60 mins by cell free tubulin polymerization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609721(CHEMBL5270408)
Affinity DataKd:  4.49E+3nMAssay Description:Binding affinity to porcine brain tubulin assessed as changes in the fluorescence incubated for 10 mins tryptophan-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed