BDBM50609720 CHEMBL5285469

SMILES [H][C@@]12Cc3cc4OCCOc4cc3[C@H](N1C(=O)NC2=O)c1cc(Br)c(OC)c(Br)c1

InChI Key InChIKey=JLVXITSDGMVAMK-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609720   

TargetTubulin beta chain(Pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609720(CHEMBL5285469)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of porcine brain tubulin assessed as changes in the fluorescence intensity measured for 60 mins by cell free tubulin polymerization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTubulin beta chain(Pig)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609720(CHEMBL5285469)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to porcine brain tubulin assessed as changes in the fluorescence incubated for 10 mins tryptophan-based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed