BDBM50609589 CHEMBL5282652

SMILES Cc1cc(\C=C\C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)c(F)c2)nc2COCc12

InChI Key InChIKey=NXWBHECFJJKVHJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609589   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50609589(CHEMBL5282652)
Affinity DataKd:  2.50E+3nMAssay Description:Binding affinity to HIV-1 reverse transcriptase assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50609589(CHEMBL5282652)
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type recombinant HIV-1 reverse transcriptase using biotin-labelled dNTPs as substrate assessed as inhibition of biotin-labelled UT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed