BDBM50609562 CHEMBL5291380

SMILES COc1cc(C)c(Cl)cc1S(=O)(=O)Nc1ccc2N(CCCc2c1)C(=O)N(C)C

InChI Key InChIKey=NHUYRIDWSHPVGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50609562   

TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609562(CHEMBL5291380)
Affinity DataIC50: 2.75E+3nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by Lanthascreen TR-FRET competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609562(CHEMBL5291380)
Affinity DataIC50: 50nMAssay Description:Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of TNF-alp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609562(CHEMBL5291380)
Affinity DataIC50: 530nMAssay Description:Modulation of glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as transrepression by measuring inhibition of PMA-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50609562(CHEMBL5291380)
Affinity DataIC50: 2.73E+4nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin) transfected in human HeLa cells assessed as inhibition of dexamethasone-induced trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed