BDBM50609521 CHEMBL5283602

SMILES CC(C)c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(C)ccc2[nH]ncc12

InChI Key InChIKey=YRLUHGPJSFPQKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50609521   

TargetGTPase KRas(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50609521(CHEMBL5283602)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 6 hrs by MSD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed