BDBM50609442 CHEMBL5266396

SMILES CC(C)Oc1cc(C2CCNCC2)c(C)cc1Nc1ncc(Cl)c(Nc2cccc3COB(O)c23)n1

InChI Key InChIKey=WIIZIOIRVCPAGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50609442   

TargetALK tyrosine kinase receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50609442(CHEMBL5266396)
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal GST-tagged human wild type ALK cytoplasmic domain (1058 to 1620 residues) expressed in baculovirus-infected Sf21 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50609442(CHEMBL5266396)
Affinity DataIC50: 35nMAssay Description:Inhibition of N-terminal GST-tagged human ALK cytoplasmic domain (1058 to 1620 residues) C1156Y mutant expressed in baculovirus-infected Sf21 cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50609442(CHEMBL5266396)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of N-terminal GST-tagged human ALK cytoplasmic domain (1058 to 1620 residues) L1196M mutant expressed in baculovirus-infected Sf21 cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed