BDBM50609425 CHEMBL5280243

SMILES CC(C)n1ncc2c(cc(cc12)-c1ccc(nc1)N1CCN(CCNC(=O)CCOCCNc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=LRMNSTSNSCJHGZ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50609425   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609425(CHEMBL5280243)
Affinity DataEC50:  200nMAssay Description:Induction of degradation of EZH2 in human EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609425(CHEMBL5280243)
Affinity DataEC50:  1.50E+3nMAssay Description:Induction of degradation of EZH2 in human MV4-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609425(CHEMBL5280243)
Affinity DataIC50: 7nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed