BDBM50609394 CHEMBL5266076

SMILES COC(=O)c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)CC(C)(C)C)cc1

InChI Key InChIKey=LUXKEEIMLQRZAH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609394   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50609394(CHEMBL5266076)
Affinity DataIC50: 5.32E+4nMAssay Description:Binding affinity to VHL E3 ligase (unknown origin) by fluorescence polarization (FP) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50609394(CHEMBL5266076)
Affinity DataKd:  4.55E+4nMAssay Description:Binding affinity to VHL E3 ligase (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed