BDBM50609374 CHEMBL5274383

SMILES Oc1ccc(\C=C2/Cc3ccccc3C2=O)c(O)c1

InChI Key InChIKey=RBDZAUOXRXNMMO-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50609374   

TargetPolyphenol oxidase 2(White button mushroom)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50: 34nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTyrosinase(Human)
University Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates using L-DOPA as substrate assessed as reduction in melanin formation preincubated for 10 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Universite Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50609374(CHEMBL5274383)
Affinity DataKi:  2.40nMAssay Description:Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as inhibition constant incubated for 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed