BDBM50609297 CHEMBL5285673

SMILES CC[C@H]1CN(C[C@H]1Nc1c(cnn2cc(nc12)-c1cnn(C)c1)C(N)=O)c1ccc(cn1)C#N

InChI Key InChIKey=HVOHXBGDKYDBQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609297   

TargetTyrosine-protein kinase JAK1(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50609297(CHEMBL5285673)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of GST-fused human JAK1 incubated for 3 hrs by caliper analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Universite de Tours

Curated by ChEMBL
LigandPNGBDBM50609297(CHEMBL5285673)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant JAK3 incubated for 3 hrs by caliper analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed