BDBM50609291 CHEMBL5281874

SMILES CC(=O)Nc1cn2nc(ccc2n1)-c1cnc(Cl)c(NS(=O)(=O)N2CCOCC2)c1

InChI Key InChIKey=UCXPQJNZIRTUGH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609291   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Universite de Tours

Curated by ChEMBL

LigandBDBM50609291(CHEMBL5281874)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
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TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Universite de Tours

Curated by ChEMBL

LigandBDBM50609291(CHEMBL5281874)Copy SMILESCopy InChI

Affinity DataIC50: 75nMAssay Description:Inhibition of Akt phosphorylation in human HCT-116 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL