BDBM50609144 CHEMBL5279863

SMILES CC(C)(O)C#Cc1cc2n(cc(C3CCOCC3)c2cn1)-c1ccnc(N)n1

InChI Key InChIKey=LBUHKZDYNWJSLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609144   

TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609144(CHEMBL5279863)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609144(CHEMBL5279863)
Affinity DataIC50: 164nMAssay Description:Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed