BDBM50609139 CHEMBL5280803

SMILES COc1cc2ccn(-c3ccnc(N)n3)c2cc1C#CC(C)(C)O

InChI Key InChIKey=VNKYVVIEELPQIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50609139   

TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609139(CHEMBL5280803)
Affinity DataIC50: 39nMAssay Description:Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetTau-tubulin kinase 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50609139(CHEMBL5280803)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed