BDBM50608701 CHEMBL5275735

SMILES COc1ccc(\C=C2\SC(=S)C(Nc3nc4n(ncc4c(=O)n3-c3ccccc3)-c3ccccc3)C2=O)cc1OC

InChI Key InChIKey=VZFSDYNQLFGJKX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50608701   

TargetProstaglandin G/H synthase 1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608701(CHEMBL5275735)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of COX-1 (unknown origin) at 40 uM relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608701(CHEMBL5275735)
Affinity DataIC50: 370nMAssay Description:Inhibition of COX-2 (unknown origin) assessed as inhibition at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608701(CHEMBL5275735)
Affinity DataIC50: 780nMAssay Description:Inhibition of COX-2 (unknown origin) at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed