BDBM50608680 CHEMBL5282224

SMILES [O-][N+](=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3)c(nc2c1)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=FMXPLCOPRJODRZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50608680   

TargetProstaglandin G/H synthase 2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 320nMAssay Description:Inhibition of 5-LOX (unknown origin) after 5 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 9.85E+3nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50608680(CHEMBL5282224)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of 15-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed