BDBM50608638 CHEMBL4303684::US20240091210, Compound UK5099

SMILES OC(=O)C(=C\c1cn(-c2ccccc2)c2ccccc12)\C#N

InChI Key InChIKey=BIZNHCWFGNKBBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50608638   

TargetMonocarboxylate transporter 1(Rat)
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Curated by ChEMBL
LigandPNGBDBM50608638(CHEMBL4303684 | US20240091210, Compound UK5099)
Affinity DataIC50: 13nMAssay Description:Inhibition of MCT1 in rat Brain-like endothelial cells incubated for 15 mins in presence of [14C]lactic acid by scintillation counter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandPNGBDBM50608638(CHEMBL4303684 | US20240091210, Compound UK5099)
Affinity DataIC50: 1.70E+4nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent