BDBM50608601 CHEMBL5284688

SMILES COc1ccc(cc1)S(=O)(=O)N1CCCC(C)(C)CC1C(=O)NO

InChI Key InChIKey=WMYJDFANEQLDGP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50608601   

TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608601(CHEMBL5284688)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human MMP1 expressed in Escherichia coli BL21 (DE3) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608601(CHEMBL5284688)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human full length MMP2 using Mca-Pro-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20 to 30 mins by fluorescence microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608601(CHEMBL5284688)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human MMP3 expressed in Escherichia coli BL21 (DE3) using [3H]transferrin as substrate incubated for 3 hrs by scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608601(CHEMBL5284688)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human MMP7 using Mca-Pro-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20 to 30 mins by fluorescence microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608601(CHEMBL5284688)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of recombinant human MMP8 using Mca-Pro-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20 to 30 mins by fluorescence microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608601(CHEMBL5284688)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human MMP9 using Mca-Pro-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 20 to 30 mins by fluorescence microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed