BDBM50608588 CHEMBL437017

SMILES COc1ccc(cc1)S(=O)(=O)[N@]2CN(C(=O)C[C@@H]2C(=O)NO)Cc3ccccc3

InChI Key InChIKey=SUSMVCKSLVPRCL-UHFFFAOYSA-N

Data  7 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50608588   

TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 22nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Rat)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of rat MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50608588(CHEMBL437017)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed