BDBM50608584 CHEMBL5275885

SMILES CCOC(=O)C1=Cc2ccc(cc2N=C(N)C1)-c1cccc(c1)C#N

InChI Key InChIKey=YHRYTTWRVKXODS-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50608584   

TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at human TLR8 transfected in HEK-Blue hTLR8 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at human TLR7 transfected in HEK-Blue hTLR7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  30nMAssay Description:Agonist activity in TLR8 (unknown origin) expressed in HEK293 cells assessed as induction of NF-kappa activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  1.50E+4nMAssay Description:Agonist activity at TLR8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetToll-like receptor 7(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50608584(CHEMBL5275885)
Affinity DataEC50:  30nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed