BDBM50608416 CHEMBL5269448

SMILES OC1(Cn2cnc3n(ncc3c2=O)-c2ccc(F)cc2)CCN(CC1)C(=O)c1ccc(cc1)-c1ccccc1NS(=O)(=O)C=C

InChI Key InChIKey=FMQKBLFJHXUHMS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50608416   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50608416(CHEMBL5269448)
Affinity DataIC50: 65nMAssay Description:Inhibition of human USP7 by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50608416(CHEMBL5269448)
Affinity DataKd:  7.80E+3nMAssay Description:Inhibition of human his tagged USP7 (208 to 560 residues) expressed in insect sf9 cells using monoubiquitinated ubiquitin-rhodamine as substrate asse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed